Deep dives into diseases, medical breakthroughs, scientific innovations, finance, and the stories shaping our world.
How two scientists spent decades developing a technology no one believed in, then used it to create COVID-19 vaccines in record time.
Superbugs kill 5 million people yearly. New antibiotics could save them. So why have 15 of the 18 largest drug companies abandoned antibiotic research?
The FDA is rejecting drugs tested only in China. What does this mean for global drug development, and does a trial in Shanghai tell us anything about patients in Seattle?
It costs $2 billion and 10-15 years to bring a drug to market. Only 12% of drugs that enter trials succeed. Here's why pharmaceutical economics is so brutal.
Apple and Google built privacy-preserving exposure notification in weeks. It could have transformed pandemic response. Here's why it didn't.
How a Cold War defense project became the backbone of modern civilization, connecting billions of people and reshaping every aspect of human life.
Gold has shattered all-time records in 2024-2025, surpassing $4,000 per ounce. What's driving the surge, and what does history tell us about where it might go next?
How the discovery of a single gene led to breakthrough therapies that are transforming life for people with CF: a triumph of molecular medicine.
Found in soil and water everywhere, this versatile bacterium is harmless to most people. But for those with cystic fibrosis or weakened immune systems, it's one of the deadliest infections known.
The Nobel Prize-winning discovery that tumors hide from immune attack, and how blocking these "checkpoints" has transformed cancer treatment while creating new cardiac risks.
In 1978, scientists inserted human genes into bacteria and created medicine. This first recombinant drug launched a revolution that continues to transform healthcare.
Breaking biology's "central dogma," retroviruses reverse the flow of genetic information, turning RNA into DNA and inserting themselves permanently into host chromosomes.
Through antigenic drift and shift, influenza constantly reinvents itself, evading immunity, causing annual epidemics, and occasionally spawning pandemics that kill millions.
Neither virus nor bacterium, prions are misfolded proteins that cause invariably fatal brain diseases. They challenged everything we thought we knew about infection.
Your immune system is designed to protect you from threats. In allergies, it misfires, attacking harmless pollen, foods, or pet dander as if they were deadly pathogens.
How DeepMind cracked the 50-year-old protein folding problem, transforming structural biology and earning the 2024 Nobel Prize in Chemistry.
How Kary Mullis's late-night brainstorm led to polymerase chain reaction: the technique that revolutionized molecular biology, forensics, and medicine.
From Frederick Sanger's elegant chemistry to machines that sequence entire genomes in hours: the remarkable evolution of DNA sequencing technology.
From a cluster of pneumonia cases in Wuhan to a global pandemic that reshaped society: the science, the response, and the lessons we must learn.
The story of humanity's confrontation with HIV: from mysterious deaths in 1981 to antiretroviral therapy that now allows people to live normal lifespans.
Despite sharing a name, hepatitis A, B, and C are different viruses with distinct histories, including the Nobel Prize-winning discovery of HCV and its cure.
How the most contagious disease known to humanity went from killing 2.6 million children annually to near elimination, and why it is coming back.
How a devastating waterborne disease led to the birth of epidemiology, the germ theory of disease, and modern sanitation.
From Alois Alzheimer's first patient to the controversial new treatments: understanding the most common cause of dementia.
From James Parkinson's 1817 essay to modern deep brain stimulation: understanding the disease that affects movement, mood, and mind.
How a diabetes medication became the most talked-about drug of the decade, and what GLP-1 agonists mean for the future of obesity treatment.
From a death sentence to a manageable condition: the history, science, and future of one of humanity's most common chronic diseases.
Cardiovascular disease claims more lives than any other cause, nearly 18 million annually. From the discovery of cholesterol to modern interventions.
Formerly known as NASH, metabolic dysfunction-associated steatohepatitis is becoming the leading cause of liver transplants, and most people have never heard of it.
How the poliovirus attacks the nervous system, the heroes who developed the vaccines, and why we're so close to making it the second disease ever eradicated.
The only human disease ever eradicated, smallpox killed an estimated 300 million people in the 20th century. The story of how we defeated it.
Plasmodium parasites have been killing humans for over 50,000 years. Despite new vaccines, malaria still claims over 600,000 lives annually.
TB infects a quarter of the world's population and remains one of the deadliest infectious diseases. Why can't we end it?
With fatality rates up to 90%, Ebola hemorrhagic fever is one of the most lethal diseases known. The 2014-2016 epidemic changed global health security.
Methicillin-resistant Staphylococcus aureus represents one of the greatest threats of the antibiotic resistance era.
Group A Streptococcus causes everything from strep throat to necrotizing fasciitis, responsible for over 500,000 deaths annually.
About 30% of people carry Staph aureus without symptoms. But when it invades, it can cause life-threatening infections.